The MTB Portal Interprets Cancer Genomic Variants

This is a research version of the MTB Portal that provides a general framework for interpreting the functional and predictive relevance of a given list of gene variants through interactive reports .

The MTB Portal uses distinct levels of supporting evidence

Variants are annotated using multiple knowledgebases , bona fide biological assumptions and computational prediction models .

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The MTB Portal follows clinical expert consensus

The variant annotation is based on established expert agreement .

About us

This is an open access version of the Molecular Tumor Board Portal (MTBP) that provides a general interpretation for a given list of cancer gene variants. The portal uses a number of computational tools and databases that are referenced (and linked when appropriate) in the provided results. Note that some of these resources require a license agreement for their use in commercial systems and/or for patient services such as clinical reporting, and thus the open MTBP cannot be used for any of these purposes but must be strictly limited to academic research use only. These terms of use must be accepted after the first login into the system, which requires the use of a valid email address. When using the MTB portal, please cite: Tamborero D, Dienstmann R et al. Nature Medicine 2020 and/or Tamborero D et al. Nature Cancer 2022 .